Royal Air Force Typhoon jets have joined forces with France's air force in a coordinated attack on an underground arms cache in Syrian territory operated by the IS group, as stated by the UK's MoD.
The site, pinpointed through intelligence, was believed to be storing arms and explosives, the release indicated, and was situated in mountains just above Palmyra in central Syria.
"Our fighter planes utilized Paveway IV guided bombs to strike a several entry passages leading to the depot... initial indications are that the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the strike conducted Saturday night and each participating jet made a safe return, the ministry further stated.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
The Islamic State group - also known as ISIS - enforced militant control over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This strike underscores our UK leadership, and determination to operate in unison with our partners, to stamp out any revival of IS and their violent and radical beliefs in the region," UK Defence Secretary John Healey remarked.
British military aircraft have carried out surveillance missions over Syrian airspace to "forestall any attempted resurgence" of IS after its routing at the battle of Baghuz in 2019, the authorities noted.
"I want to thank the personnel of our armed forces who took part in this strike for their professionalism and their valour," the Defence Secretary said. "They were among numerous British personnel on duty over the holidays. This operation, to take out terrorist threats who pose a risk to our way of life, demonstrates how our armed forces are ready to step up, continuously, keeping Britain secure domestically and strong abroad."
Last December, the United States armed forces executed what it called a "major assault" on Daesh sites in the country, following an assault claimed the lives of two American soldiers and a civilian interpreter in Palmyra.
The UN reports Daesh still boasts an estimated 5,000 to 7,000 fighters in Syria and Iraq.